Etiologic Pathogenesis of Melanoma: Fig. 1.

Etiologic pathogenesis of melanoma: a unifying hypothesis for the missing attributable risk.

Melanoma is the eighth most common malignancy in the United States and has shown rapid increases in its incidence rate over the past two decades, especially in early-stage disease (1–4). A recent analysis of data from the Surveillance Epidemiology and End Results Program indicates that the incidence of melanoma increases with age, with somewhat different patterns in men and women (3). Genetic a...

Fig. 1

Pathogenesis of Malignant Melanoma

It has long been known that cancer arises most frequently from cells in tissues which undergo constant renewal [12]. For example, epithelial tissues of the skin and intestine are composed of cells which are renewed throughout life and are also often the source of adult malignancies [4, 64]. Although the process is periodic rather than constant, melanocytes also undergo frequent renewal and thus...

Etiologic and other factors predicting nevus-associated cutaneous malignant melanoma.

Cutaneous malignant melanomas with histologic evidence of an associated nevus (N+) may have a different risk factor profile from that of melanomas without it (N-). To address this question, a case-only analysis of 932 people with cutaneous malignant melanoma was done to identify etiologic and other factors associated with N+ melanoma. Evidence of an associated nevus was found in 36% of melanoma...

Fig. 1: Mpeg-4 Coding Scheme

A programmable processor architecture for MPEG-4 video is proposed, that can serve as a coprocessor module in MPEG-4 decoder systems. It consists of a 64-bit dual-issue VLIW macroblock engine, a separate RISC core for bitstream parsing and system processing, and an autonomous I/O processor. A separate DSP is used for MPEG audio support. The architecture is fully programmable and supports parall...